Dr David Smith
Research groups
- Combining infectious disease and economic modelling to inform which antimicrobial resistance-related interventions to prioritise to optimise overall population health and reduce inequalities
- Combining infectious disease and economic modelling to inform international decision making around antibiotic use targets and implementation of interventions aimed at ensuring continued successful treatment of bacterial infections
David Smith
MSc, PhD
Senior Researcher
David joined the Health Economics Research Centre (HERC) as a senior researcher in February 2023.
His current research involves the development of health-economic models to evaluate the efficiency of infectious disease surveillance and control interventions, with a focus on antimicrobial resistance, Covid-19 and healthcare-associated infections.
David is particularly interested in using transmission modelling within health-economic evaluations to inform intervention design, including the optimisation of SARS-CoV-2 surveillance programmes and the setting of reduction targets for inappropriate antibiotic prescribing.
Prior to joining HERC, David was based at Institut Pasteur in France, where he used transmission modelling to study various topics in nosocomial infection control, including how antibiotic-induced microbiome dysbiosis impacts bacterial transmission, how testing strategies can be optimised for Covid-19 prevention, and how Covid-19 outbreaks influence the spread of antibiotic-resistant bacteria.
Previously, David worked as a mathematical modeller at Public Health England, and was involved in projects including national evaluations of inappropriate antibiotic prescribing in English primary care, and of the health-economic burden of urinary catheter-associated infection in English hospitals.
David holds a PhD in public health and biostatistics from Université Paris-Saclay, and an MSc in ecology and evolutionary biology from the University of Toronto.
Recent publications
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Health and economic impacts of Lassa vaccination campaigns in West Africa
Journal article
Smith D. et al, (2024), Nature Medicine
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Climate change, malaria and neglected tropical diseases: a scoping review.
Journal article
Klepac P. et al, (2024), Trans R Soc Trop Med Hyg
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Antimicrobial Resistance as Risk Factor for Recurrent Bacteremia after Staphylococcus aureus, Escherichia coli, or Klebsiella spp. Community-Onset Bacteremia.
Journal article
Abbara S. et al, (2024), Emerg Infect Dis, 30, 974 - 983
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Exploring factors shaping antibiotic resistance patterns in Streptococcus pneumoniae during the 2020 COVID-19 pandemic
Journal article
Kovacevic A. et al, (2024), eLife, 13
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Predicting consequences of COVID-19 control measure de-escalation on nosocomial transmission and mortality: a modelling study in a French rehabilitation hospital
Journal article
Smith DRM. et al, (2024), Journal of Hospital Infection