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Direct acting antiviral therapy is a highly effective treatment for hepatitis C virus (HCV), yet access remains limited on a global scale. Over the past few years, researchers have started to implement clinical trials in LMICs to test the medication in different contexts and for different durations, thereby providing access to treatment for a segment of the population.

In this talk, I discuss the design and preliminary findings of an ethnographic study taking place alongside an HCV treatment trial at Hospital for Tropical Diseases in Ho Chi Minh City, Vietnam. In this study, we examine the care and treatment experiences of a subset of the trial participants, as well as their perceptions of health and illness related to HCV. The study started in March 2019 and recruitment, enrollment and data collection are ongoing. We plan to enroll 18-21 trial participants into the study. We will conduct two in-depth interviews with the participants at the study site (i.e. the first on Day 0, the second at the last study visit) and one mobile interview in their community. We will use participant observation at the study site and at the outpatient HCV clinic throughout the trial to engage with both participants and healthcare staff.

This study builds on research that I conducted in Rwanda from 2016-2018 where we collected in-depth interviews with 11 study participants over the course of an HCV treatment study. I will discuss four interconnected themes that we identified during data analysis as a background for the Vietnam study: 1) understanding of diagnosis and use of traditional medicine, 2) access and financial barriers to care-seeking, 3) complex social networks, 4) proactivity in care-seeking.

Finally, I explore preliminary findings from the Vietnam study including community discourse surrounding hepatitis C, individual care seeking experiences, and issues related to participation in clinical trials. To conclude, I discuss the wider implications of integrating ethnographic research in clinical trials, on both local and global levels.


Forthcoming events

Methodological Issues in Nutritional Epidemiology and the Assessment of Preventable Mortality

Tuesday, 17 September 2019, 2pm to 3pm @ Richard Doll Lecture Theatre, Richard Doll Building, Old Road Campus, OX3 7LF

Mini-Symposium: Large prospective studies of diet and health: research in the Nuffield Department of Population Health

Tuesday, 17 September 2019, 3.30pm to 5pm @ Richard Doll Lecture Theatre, Richard Doll Building, Old Road Campus, OX3 7LF

Ethox/WEH Seminar - Newborn Screening for Sickle Cell Disease in Tanzania: Understanding ethical, social and resource based implications

Wednesday, 18 September 2019, 11am to 12.30pm @ Seminar room 0, BDI, Old Road Campus, OX3 7LF

Oxford-Peking University Joint Symposium on Precision Medicine

Thursday, 19 September 2019, 10am to 6pm @ Seminar rooms, BDI, Old Road Campus, OX3 7LF

CKB Workshop - Infections, immunity and cancer: aetiology and beyond

Friday, 20 September 2019, 1pm to 5pm @ Seminar rooms, BDI, Old Road Campus, OX3 7LF