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ABSTRACT

Direct acting antiviral therapy is a highly effective treatment for hepatitis C virus (HCV), yet access remains limited on a global scale. Over the past few years, researchers have started to implement clinical trials in LMICs to test the medication in different contexts and for different durations, thereby providing access to treatment for a segment of the population.

In this talk, I discuss the design and preliminary findings of an ethnographic study taking place alongside an HCV treatment trial at Hospital for Tropical Diseases in Ho Chi Minh City, Vietnam. In this study, we examine the care and treatment experiences of a subset of the trial participants, as well as their perceptions of health and illness related to HCV. The study started in March 2019 and recruitment, enrollment and data collection are ongoing. We plan to enroll 18-21 trial participants into the study. We will conduct two in-depth interviews with the participants at the study site (i.e. the first on Day 0, the second at the last study visit) and one mobile interview in their community. We will use participant observation at the study site and at the outpatient HCV clinic throughout the trial to engage with both participants and healthcare staff.

This study builds on research that I conducted in Rwanda from 2016-2018 where we collected in-depth interviews with 11 study participants over the course of an HCV treatment study. I will discuss four interconnected themes that we identified during data analysis as a background for the Vietnam study: 1) understanding of diagnosis and use of traditional medicine, 2) access and financial barriers to care-seeking, 3) complex social networks, 4) proactivity in care-seeking.

Finally, I explore preliminary findings from the Vietnam study including community discourse surrounding hepatitis C, individual care seeking experiences, and issues related to participation in clinical trials. To conclude, I discuss the wider implications of integrating ethnographic research in clinical trials, on both local and global levels.

 

Forthcoming events

Title TBC

Monday, 15 April 2024, 1pm to 2pm @ BDI/OxPop Building LG seminar rooms

The effects of BCG on non-specific resistance to respiratory infection

Monday, 13 May 2024, 1pm to 2pm @ BDI/OxPop Building LG seminar rooms

Title TBC

Monday, 20 May 2024, 1pm to 2pm @ BDI/OxPop Building LG seminar rooms