Can we use genomics to identify new causes of cancer?
Dr Paul Brennan, Head of Genomic Epidemiology at the International Agency for Research on Cancer
Richard Doll Seminars
Tuesday, 06 June 2023, 1pm to 2pm
About 40% of the cancer burden in high income countries can be explained by known risk factors, although international differences in incidence point to other unknown causes. Several established carcinogens leave specific mutation patterns in the cancer genome, ie mutational signatures. This suggests that sequencing large numbers of tumour samples from different populations may be a useful strategy to identify novel causes of cancer.