I am currently performing genome-wide association studies using the China Kadoorie Biobank data. The phenotypic, genetic and environment variances were collected and standardised. We are investigating the genetic causes of trait variation within and between populations.
I graduated in bioinformatics (PhD) at the National Institute for Medical Research, MRC. After working in Biomathematics & Statistics Scotland, I went to the Institute of Psychiatry, King’s College, London. I joined NDPH in early 2016.
My former research interests include protein structure prediction, protein residue contact prediction and Bayesian network modelling of gene expression.
Identification of type 2 diabetes loci in 433,540 East Asian individuals
WALTERS R. et al, (2020), Nature
Genetic Predisposition to Type 2 Diabetes and Risk of Subclinical Atherosclerosis and Cardiovascular Diseases Among 160,000 Chinese Adults.
Gan W. et al, (2019), Diabetes, 68, 2155 - 2164
Associations of autozygosity with a broad range of human phenotypes.
Clark DW. et al, (2019), Nat Commun, 10
Inflammation implicated in the aetiology of major vascular and non-vascular diseases in East Asians
Karim M. et al, (2019), EUROPEAN HEART JOURNAL, 40, 3383 - 3383
Insights from the largest genetic study of sporadic and recurrent miscarriage
Laisk T. et al, (2019), EUROPEAN JOURNAL OF HUMAN GENETICS, 27, 1045 - 1046