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In this talk, I will explore the impact of low-frequency mutations on the evolution of drug-resistant HIV, highlighting our breakthroughs with the AMPHEUS system and veSEQ pipeline for advanced genomic analyses. Our findings reveal crucial insights into the underestimated prevalence of transmitted NRTI resistance, underscoring the urgent need for enhanced surveillance in areas with high treatment failure rates.

David Bonsall is a pioneer of pathogen genomics, leads efforts to unravel the complexities of drug resistant HIV, leveraging cutting-edge technologies to inform global health strategies.

Forthcoming events

The ecology and evolution of microbial communities

Monday, 13 January 2025, 1pm to 2pm @ BDI/OxPop Building LG seminar rooms

Health and economic impacts of Lassa vaccination campaigns in West Africa

Monday, 20 January 2025, 1pm to 2pm @ BDI/OxPop Building LG seminar room

Host-parasite interactions

Monday, 27 January 2025, 1pm to 2pm @ BDI/OxPop Building LG seminar rooms

Marburg vaccine trial

Monday, 03 February 2025, 1pm to 2pm @ BDI/OxPop Building LG seminar rooms

Tuberculosis vaccine R&D and human challenge models

Monday, 10 February 2025, 1pm to 2pm @ BDI/OxPop Building LG seminar rooms

Shingles vaccine and dementia, and other links between infectious diseases and brain health

Monday, 24 February 2025, 1pm to 2pm @ BDI/OxPop Building LG seminar rooms