Daniel Chapman
PhD
Senior Research Associate
Daniel Chapman is a Senior Research Associate in Assay Development based in the Wolfson Laboratory within the Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU), Oxford Population Health.
He has led immunoassay development, biomarker stability studies and pre-analytical validation, contributing to major randomised trials and population studies including EASi-KIDNEY, REVEAL, STICS, EMPA-Kidney, HARP-3 (UK) and the China Kadoorie Biobank.
His research focuses on the development of high-throughput quantitative and multiplex biomarker assays across multiple analytical platforms, including plate-based immunoassay and targeted mass spectrometry. To support this, he develops liquid handling automation workflows and laboratory informatics systems to improve the robustness, scalability and traceability of biomarker measurement. His work includes the structured application of AI-assisted tools.
He has a particular interest in translating proteomic findings into quantitative assays suitable for large clinical trials and epidemiological studies.
Prior to joining CTSU, Daniel completed a PhD in Clinical Biochemistry and Clinical Research at the University of Exeter.
Key publications
Effects of Empagliflozin on Kidney and Cardiac Magnetic Resonance Imaging Measures in Patients With CKD: An EMPA-KIDNEY Mechanistic Substudy.
Journal article
Zhu D. et al, (2025), Am J Kidney Dis
Glucose Interference in Urine Biomarkers and Implications for Sodium-Glucose Cotransporter 2 Inhibition.
Journal article
Malijan GB. et al, (2025), Kidney Int Rep, 10, 4090 - 4093
Glucose interference in urine biomarkers and implications for SGLT2 inhibition
Journal article
Malijan G. et al, (2025), Kidney International Reports
Interference of urinary albumin-to-creatinine ratio measurement by glycosuria: clinical implications when using SGLT-2 inhibitors.
Journal article
Chapman D. et al, (2023), Kidney Int, 103, 787 - 790
Stability of urinary albumin and creatinine after 12 months storage at -20 °C and -80 °C.
Journal article
Chapman DP. et al, (2019), Pract Lab Med, 15
Recent publications
Effects of Empagliflozin on Kidney and Cardiac Magnetic Resonance Imaging Measures in Patients With CKD: An EMPA-KIDNEY Mechanistic Substudy.
Journal article
Zhu D. et al, (2025), Am J Kidney Dis
Glucose Interference in Urine Biomarkers and Implications for Sodium-Glucose Cotransporter 2 Inhibition.
Journal article
Malijan GB. et al, (2025), Kidney Int Rep, 10, 4090 - 4093
Effects of Empagliflozin on Urine Biomarkers in EMPA-KIDNEY.
Journal article
Malijan GB. et al, (2025), Am J Kidney Dis
Glucose interference in urine biomarkers and implications for SGLT2 inhibition
Journal article
Malijan G. et al, (2025), Kidney International Reports
