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OBJECTIVE: To assess obstetric and neonatal outcomes in women with a prior episode of cancer. METHODS: Data were obtained from a linkage between the Scottish Cancer Registry and routinely collected data from Scottish maternity hospitals. Obstetric outcomes in a first pregnancy which ended between 1980 and 2005 were compared in 917 women with, and 5,496 women without, a previous history of cancer. RESULTS: The mean age at delivery was 29 years (standard deviation 5.66) and 26 years (standard deviation 5.62) in the exposed and unexposed groups respectively (P<.001). Multiple logistic regression showed that cancer survivors had higher rates of postpartum hemorrhage (odds ratio [OR] 1.56, 95% confidence interval [CI] 1.09-2.23) and operative or assisted delivery (abdominal or vaginal) (OR 1.33, 95% CI 1.14- 1.54). Preterm delivery (at less than 37 weeks of gesation) was also found to be higher in this group compared with non-cancer women (OR 1.33, 95% CI 1.01-1.76). CONCLUSION: While largely reassuring to women intending to become pregnant after surviving cancer, the results indicate areas of increased risk that require additional surveillance.

Original publication




Journal article


Obstet Gynecol

Publication Date





849 - 854


Age of Onset, Cohort Studies, Delivery, Obstetric, Female, Humans, Maternal Age, Neoplasms, Pregnancy, Pregnancy Complications, Pregnancy Outcome, Retrospective Studies, Survivors, United Kingdom