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David Matthews is the Emeritus Founding Chairman of OCDEM and Professor of Diabetic Medicine at the University of Oxford, past NIHR Senior Investigator and Founding Director of the Oxford Health Alliance. He is currently Dean of Harris Manchester College, Oxford. He chaired the EASD/ADA group that produced the international guidelines on the treatment of type 2 diabetes – both in 2012 and in 2015.

His research interests include personalised medicine, the aetiopathology and treatment of type 2 diabetes, modelling of insulin resistance, the incretin axis and glucagon-like peptide-1, pulsatile insulin secretion, and the global obesity epidemic. He previously gave the Banting Memorial Lecture at Diabetes UK (‘Type 2 diabetes: the Black Death of the 21st century’). He has authored more than 300 academic peer-reviewed publications and sits on the editorial board of several professional journals.

Major trial results over the least 3 years have demonstrated the promise of SGLT2 inhibitor therapy for cardiovascular, cardiovascular and heart failure outcomes in diabetes. Professor Matthews is co-chair of the CANVAS and CANVAS-R trials of the SGLT2 inhibitor, canagliflozin, and he will discuss the CANVAS program, and its results in this seminar.

Forthcoming events

Richard Doll Seminar: Design and analysis of prevalence surveys in low-resource settings

Tuesday, 25 February 2020, 1pm to 2pm @ Richard Doll Lecture Theatre, Richard Doll Building, Old Road Campus, OX3 7LF

WEH/Ethox Seminar

Wednesday, 26 February 2020, 11am to 12.30pm @ Seminar room 0, Big Data Institute, Old Road Campus, OX3 7LF

HERC Seminar: Learning healthcare systems for cost-effective precision oncology.

Thursday, 27 February 2020, 12pm to 1pm @ Seminar room 0, Big Data Institute, Old Road Campus, OX3 7LF

The Global Response to the Novel Coronavirus (SARS-CoV-2) Outbreak

Thursday, 27 February 2020, 2.30pm to 4pm @ Seminar rooms, Big Data Institute

Richard Doll Seminar: The Risk of Everything – using linked electronic health records to develop and validate risk prediction tools for use in clinical care

Tuesday, 03 March 2020, 1pm to 2pm @ Richard Doll Lecture Theatre, Richard Doll Building, Old Road Campus, OX3 7LF

WEH/Ethox Seminar: Building research capacity through North-South Partnerships: some ethical reflections and a social justice agenda

Wednesday, 04 March 2020, 11am to 12.30pm @ Seminar room 0, Big Data Institute, Old Road Campus, OX3 7LF