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Robert Hills is Professor of Translational Statistics at the Centre for Trials Research, Cardiff University, and Lead for Clinical Cancer Research Methodology.

His interests include novel trial designs to maximise data from patients in increasingly genetically delineated conditions, and meta-analyses of data from different trials, including a recent individual patient data meta-analysis of gemtuzumab ozogamicin (mylotarg) which has been used to support licensing applications in The United States and the EU.

Since 2006 he has worked in Cardiff as statistician for the NCRI Trials in Acute Myeloid Leukaemia, including introducing the multi-arm multi-stage Pick-A-Winner design for older patients not suitable for intensive chemotherapy, which has so far accumulated data on a dozen comparisons. The NCRI AML trials have also accumulated over 10,000 samples, which has allowed investigations of both prognostic and predictive markers. These results have enabled improved risk stratification and the identification of patients who are not well served by current therapy.

In his talk he will explore the story of Mylotarg, from the first randomised controlled trial (AML15) in 2002 through to the recent approval by the FDA last autumn, including the role of the IPD meta-analysis.

Forthcoming events

Oxford-Peking University Joint Symposium on Precision Medicine

Thursday, 19 September 2019, 10am to 6pm @ Seminar rooms, BDI, Old Road Campus, OX3 7LF

CKB Workshop - Infections, immunity and cancer: aetiology and beyond

Friday, 20 September 2019, 1pm to 5pm @ Seminar rooms, BDI, Old Road Campus, OX3 7LF

NDPH Seminar - Changing the way medical research is funded: Some lessons from Australia

Thursday, 26 September 2019, 4pm to 5pm @ Seminar rooms, BDI, Old Road Campus, OX3 7LF

Ethox/WEH Seminar - Reclaiming a Sense of Common Humanity: A Confucian Ethical Vision

Wednesday, 02 October 2019, 11am to 12.30pm @ Level 1 Ax Meeting Room, BDI, Old Road Campus, OX3 7LF

UVBO Seminar - Can wearable sensors and machine learning enhance our understanding of lifestyle health behaviours?

Thursday, 17 October 2019, 1pm to 2pm @ L1 Meeting room, Richard Doll Building, Old Road Campus, OX3 7LF

UVBO Seminar - Nutrient timing and human health

Thursday, 24 October 2019, 1pm to 2pm @ School of Anthropology, 61 Banbury Road, OX2 6PE