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Abstract

Caroline Relton obtained a PhD in molecular genetics at Newcastle University in 1999 where she then held an academic position for 12 years, before moving to the University of Bristol in 2012. Caroline’s research focuses on understanding the role of both genetic and epigenetic variation in development and disease. The work of her group includes using population-based approaches to study epigenetic information as a biomarker of exposure and a predictor of disease. She has developed and applied causal analysis methods to understand the role of epigenetic processes as disease mechanisms and has led studies investigating the genetic architecture of DNA methylation variation. Her research spans multiple clinical areas from perinatal health to cancer. Caroline is also Director of the Bristol Population Health Science Research Institute.

This lecture will provide some background as to why the fusion of epigenetics and epidemiology may be a fruitful avenue of enquiry in biomedical research, what sorts of questions we can consider addressing, what some of the challenges are and describe some of the solutions that we have developed.

Forthcoming events

Infectious Disease Seminar Series: Hepatitis B diagnosis, prevention and treatment: laboratory approaches to the elimination agenda

Monday, 06 February 2023, 1pm to 2pm @ BDI Seminar Room LG 0-1, Old Road Campus, Headington, OX3 7LF

Ethox seminar- Feminist-Ethical Perspectives on Digital (Health) Technologies

Tuesday, 14 February 2023, 11am to 12.30pm @ Big Data Institute, Lower Ground Seminar Room 1, Oxford Population Heath, University of Oxford

Richard Doll Seminar - E-Freeze trial results

Tuesday, 14 February 2023, 1pm to 2pm @ Richard Doll Lecture Theatre, Richard Doll Building, Old Road Campus, OX3 7LF

Infectious Disease Seminar Series: Informing on Neisseria gonorrhoeae treatment and management through pathogen genomics

Monday, 20 February 2023, 1pm to 2pm @ BDI Seminar Room LG 0-1, Old Road Campus, Headington, OX3 7LF