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Abstract

Caroline Relton obtained a PhD in molecular genetics at Newcastle University in 1999 where she then held an academic position for 12 years, before moving to the University of Bristol in 2012. Caroline’s research focuses on understanding the role of both genetic and epigenetic variation in development and disease. The work of her group includes using population-based approaches to study epigenetic information as a biomarker of exposure and a predictor of disease. She has developed and applied causal analysis methods to understand the role of epigenetic processes as disease mechanisms and has led studies investigating the genetic architecture of DNA methylation variation. Her research spans multiple clinical areas from perinatal health to cancer. Caroline is also Director of the Bristol Population Health Science Research Institute.

This lecture will provide some background as to why the fusion of epigenetics and epidemiology may be a fruitful avenue of enquiry in biomedical research, what sorts of questions we can consider addressing, what some of the challenges are and describe some of the solutions that we have developed.

Forthcoming events

What can genotyping studies tell us about on-farm transmission routes of Campylobacter?

Monday, 04 March 2024, 1pm to 2pm @ BDI/OxPop Building LG seminar rooms

Oxford Festival of Global Health - Lovesick

Thursday, 07 March 2024, 4pm to 8pm @ The Curzon Cinema, The Westgate, Oxford

Title TBC

Monday, 15 April 2024, 1pm to 2pm @ BDI/OxPop Building LG seminar rooms

The effects of BCG on non-specific resistance to respiratory infection

Monday, 13 May 2024, 1pm to 2pm @ BDI/OxPop Building LG seminar rooms