Leveraging vaccines to reduce antibiotic use and prevent antimicrobial resistance

Dr Mateusz Hasso-Agopsowicz is a Technical Officer in the Department of Immunization, Vaccines and Biologicals (IVB) at the World Health Organization (WHO). He holds a PhD in Vaccine Immunology from the London School of Hygiene and Tropical Medicine (LSHTM). Mateusz leads theme areas on the role of vaccines in reducing antimicrobial resistance (AMR), development of vaccine-microarray patches (MAPs) and enteric vaccines at the WHO. His work prioritises and facilitates the development of vaccines and delivery systems that will be readily used in low- and middle-income countries (LMICs).  Dr Mateusz has assessed the pipeline of vaccines in development and their value to reduce AMR to inform vaccine prioritisation during development, introduction, and use, and the selection of vaccines for the Gavi Vaccine Investment Strategy. He has also published and disseminated the WHO's strategy on leveraging vaccines to reduce AMR and antibiotic use. His research activities for vaccines with potentially high impact on AMR include research roadmaps, value proposition assessments, and documents summarising vaccines preferred product characteristics. 

Summary of talk:  

• The burden of AMR,  
• The mechanisms through which vaccines can prevent AMR 
• WHO strategies and analyses to better understand the impact of vaccines on AMR;  
• Evidence from observational studies and clinical trials on vaccine impact on AMR; 
• Evidence from modelling analyses on vaccine impact on AMR.

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