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This talk will illustrate some of the opportunities and challenges of using routinely collected data, specifically English national Hospital Episode Statistics, to trace infectious disease trends over time, both over the long term (going back 50 years) and in the more recent context of the COVID-19 pandemic. Such data can also be used to explore infectious disease variation by age, sex, geography, ethnicity and deprivation. With record-linkage of large-scale routine data spanning several decades, there are also opportunities for examining both short and long term outcomes in individuals with infectious disease, for example quantifying associations between infectious diseases and chronic disease outcomes, such as between Group A Streptococcal infection and chronic rheumatic heart disease, or glandular fever and multiple sclerosis.

Raph Goldacre is a Senior Data Scientist in the Health Data Epidemiology Group. Underpinned by strong clinical-academic networks across Oxford University Hospitals (OUH) and beyond, Raph's research collaborations aim to join the dots between health data science, epidemiological methods, and clinically-informed translational research output, by maximising the use of NHS health data to answer epidemiological questions that are the most relevant to specialist clinicians, patients, public health policy, and population health intelligence.

Raph has undertaken published studies of long-term time trends in hospitalisation and mortality (distinguishing epidemiological burden of disease, healthcare burden of disease and artefact caused by e.g. changes in coding methods), in relation to acute and chronic non-communicable diseases, hospital-recorded infections, common surgical procedures, clinical and public health interventions, and shifts in healthcare delivery. Other research collaborations include longitudinal studies of patient populations (e.g. case fatality, short/long-term hospital outcomes); studies of record-linked parent-child data to investigate associations between perinatal factors and maternal/paediatric disease; and studies of variation in mortality/morbidity by geographic region, reported ethnicity, and area-level deprivation. Much of this work feeds into cross-departmental collaborations with other research groups and projects where linkage to hospitalisation and other routine clinical data is required (e.g. Million Women Study, UK Biobank, National Perinatal Epidemiology Unit, and large clinical trials including RECOVERY).

Raph holds an MSc in Epidemiology from the London School of Hygiene & Tropical Medicine, enjoys participating in knowledge-sharing networks in the BDI/NDPH, and teaches on the NDPH MSc course in Global Health Science & Epidemiology and the BDI course in Hospital Episode Statistics.

Forthcoming events

The effects of BCG on non-specific resistance to respiratory infection

Monday, 13 May 2024, 1pm to 2pm @ BDI/OxPop Building LG seminar rooms

Festival of Global Health - The Silent Pandemic

Wednesday, 15 May 2024, 4pm to 8pm @ Curzon Oxford, Westgate Shopping Centre, Oxford OX1 1NZ

Title TBC

Monday, 20 May 2024, 1pm to 2pm @ BDI/OxPop Building LG seminar rooms

Exploiting electronic health records to improve infection management

Monday, 03 June 2024, 1pm to 2pm @ BDI/OxPop Building LG seminar rooms