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Next generation sequencing technologies (NGS) such as whole genome, whole exome, and large panels of genes, are rapidly changing the paradigm of medicine. Widespread use of NGS carries with it many ethical and practical challenges, some of which persist despite considerable debate. Whether laboratories and clinics should report variants of uncertain significance (VUS) to clinicians and/or patients, reinterpret VUS in response to the growing knowledge in the field, reissue reports to clinicians based on any revised classifications, and recontact patients, are all key unsolved issues in the clinical use of NGS. In addition, the question of whether, and to what extent, unsolicited findings (also known as incidental findings) should be returned to patients following NGS remains unanswered. In this presentation, Danya will discuss these issues, drawing on data from a systematic analysis 58 consent forms being used in the diagnostic setting to investigate their policies. 

If you would like to attend, please e-mail Jane Beinart at


Forthcoming events

The epidemiology of periportal fibrosis in the context of intestinal schistosomiasis

Monday, 09 October 2023, 1pm to 2pm @ BDI/OxPop Building seminar rooms

Defeating Meningitis by 2023 Global Roadmap

Monday, 16 October 2023, 1pm to 2pm @ BDI/OxPop Building seminar room 1

OxPop Festival of Global Health - The Cancer Conflict

Thursday, 19 October 2023, 5pm to 8pm @ Richard Doll Lecture Theatre, Richard Doll Building, Roosevelt Drive, Oxford, OX3 7LF

Cancer Treatments: trust and information

Chronic infections and risk of NCDs in Chinese adults

Monday, 30 October 2023, 1pm to 2pm @ BBDI/OxPop Building seminar rooms