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Project reference number - 0061

Principal Investigator - Sophie Pilleron, University of Oxford

Plain language summary - Thanks to advances in cancer treatment over recent years, colon cancer outcomes continue to improve. However, some groups of people have not benefited from such improvements. This is the case of older people who have poorer survival prospects. Only a few studies have investigated the potential reasons for the age differences in survival. This project seeks to improve the understanding of the difference in survival between young and older patients with colon cancer. We will specifically look at the role of patient-related characteristics such as sex, socioeconomic level and ethnicity, clinical factors such as the presence of other diseases, the stage at diagnosis, and the effect of treatment on age difference in survival. This project will ultimately contribute to narrowing the survival gap between patients of different ages with colon cancer in England.