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Inflammatory bowel disease and colorectal cancer

Inflammatory bowel disease (IBD) includes several conditions. The most common ones are ulcerative colitis (UC) and Crohn’s disease (CD).  UC causes inflammation and damage to the large bowel. [read more]

The Risk of Colorectal Cancer in individuals in Cystic Fibrosis

Cystic fibrosis (CF) is an inherited genetic disease that damages the lungs, digestive system and other systems of the body. The damage is caused by a fault in a gene ... [read more]

Variation in post-colonoscopy colorectal cancer across colonoscopy providers in the English National Health Service: A population-based cohort study – Update

Colonoscopy is the main diagnostic test used to identify colorectal (or bowel) cancer and involves a thin tube with a camera on the end of it being inserted into the bowel to look for a tumour. [read more]

Returns to theatre and failure to rescue following major resection for colorectal cancer 

Most patients with bowel cancer will have surgery. Some patients suffer complications during or after their surgery, such as infection or leakage. Patients who suffer complications may need to return to theatre to control the complication. [read more]

Understanding the relationship between surgical specialisation and outcomes following surgery for colorectal cancer

This work will look at the link between colorectal cancer 'specialisation' and the patient outcomes achieved by surgeons. It will look at the level of a surgeon's specialisation ...[read more].

Centralisation of salvage anal cancer surgery in England  

In 2004, clinical guidance was published by the National Institute for Health and Clinical Excellence (NICE) that said that patients with anal cancer should be managed in specialist hospitals with the right level of expertise. [read more]

Developing an area-based index of colorectal cancer risk for England to investigate the association between neighbourhood environment and colorectal cancer incidence

It is estimated that over 50% of bowel cancer cases in the UK can be prevented. Previous research has tended to focus on individual behaviours which have been found to increase the risk of developing bowel cancer. [read more]

Variation in post-imaging (CT-colonography) colorectal cancer across the English National Health Service: A population-based cohort study

In England, every year, around 35,000 people are diagnosed with bowel cancer. Usually, the diagnosis is made using colonoscopy, where a camera is guided though the bowel.  [read more]

ESREP Trust level variation in CRC treatment and outcome by age and deprivation

Around 43,000 people a year are diagnosed with bowel cancer in the UK. It is second only to lung cancer in cancer-related deaths. The average age of patients diagnosed with bowel cancer is over 70, but it is also a disease found in younger people. [read more]

Age disparities in colon cancer survival in England

Thanks to advances in cancer treatment over recent years, colon cancer outcomes continue to improve. However, some groups of people have not benefited from such improvements. [read more]

Identifying latent classes amongst patients with a stoma based upon their self-reported quality of life

It is estimated that there are currently over 100,000 people in the UK living with a stoma.   A stoma is where a section of the bowel is brought out through an opening that is made on the stomach area (abdomen),... [read more]

Adjuvant chemotherapy for rectal cancer: Comparative analysis of the United Kingdom and the Netherlands

It is known that giving some patients chemotherapy after surgery improves survival from colon cancer, however, it is not clear whether the same is true for rectal cancer. Use of chemotherapy after surgery for rectal cancer varies across different countries. [read more]

Quality Measures for Colorectal Cancer  (2018 Data)

The UK Colorectal Cancer Intelligence Hub (the Hub) produces annual bowel cancer metrics covering the English NHS.  These metrics count the number, type and results of bowel cancer operations.  [read more]

A comparison of colorectal cancer management and outcome in Denmark and Yorkshire

The number of patients surviving after a bowel cancer diagnosis has improved over recent decades in many European countries. Despite historically having similar survival rates to the UK, Denmark has recently seen greater improvement than the UK. This improvement follows special measures ... [read more]

The relationship between diabetes and development of renal complications during the surgical management of colorectal cancer

Developing bowel cancer is more common in people who have diabetes and diabetes also increases your risk of kidney problems. This research will look at whether people who have both diabetes and bowel cancer are more likely to develop kidney problems after cancer surgery, compared to people without diabetes. [read more]

Diabetes complications and their relationship with outcomes from colorectal cancer

Up to 20% of cancer patients also have diabetes.  Having diabetes is known to be linked with worse outcomes for patients after cancer surgery. Patients who have other health conditions related to their diabetes (complications) have a lower life expectancy and also have more frequent visits to the health ... [read more]