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Clinical trials and meta analysis 1

Module leads

Jonathan Emberson Jonathan Emberson

Richard Haynes Richard Haynes

Learning objective:

  • To understand and explain the design, conduct and statistical analysis of clinical trials and meta-analyses;
  • To be able to critically appraise publications (including protocols) related to these types of studies.


  1. Large-scale randomised evidence
  2. Trial design and conduct
  3. Clinical trials: safety and regulation
  4. Statistical methods for the analysis of clinical trials
  5. Systematic reviews: design and methods
  6. Meta-analyses of randomised trials: methods and interpretation
  7. Meta-analyses of observational studies
  8. Critical appraisal of systematic reviews
  9. Module practical