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Genetic epidemiology 1

Module leads

Jemma Hopewell Jemma Hopewell

 Martin Farrall

Learning objectives:

  • To understand the main principles, approaches and applications of human genetic epidemiology to understanding disease
  • To be able to interpret the results of genetic epidemiology studies. 

Sessions:

  1. Fundamental concepts of human genetic epidemiology
  2. Twin, segregation and linkage studies
  3. Principles of genetic association studies, family-relatedness and population stratification
  4. Genetic resources and genotype imputation
  5. Genetic associations I: candidate gene association studies
  6. Genetic associations II: genome-wide association studies
  7. Mendelian randomisation studies
  8. Next generation sequencing and beyond GWAS