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Communicable Diseases

Module leads

Brian Angus

Adrian Smith

Learning objectives

  • Describe the current epidemiological burden of HIV and malaria across the globe, and analyse the temporal, spatial and individual determinants of differences in epidemiology of both infections
  • Outline the natural history, pathogenicity and virulence of HIV and malaria in humans, and the routes and effectiveness of transmission of both infections.
  • Outline the basic principles of vaccine development, methods to assess the efficacy and population effectiveness of vaccines and summarise the prospects for vaccine-based prevention of HIV and malaria.
  • Compare and contrast approaches to the prevention of transmission of HIV and malaria, the empiric evidence quantifying the individual and population effect of prevention approaches.
  • Outline the methods of diagnosis of HIV and malaria, and their in the public health response.
  • Outline current therapies for malaria and HIV, their mechanisms of action and the empiric evidence of effectiveness of current approaches to treatment.
  • Outline the mechanisms and clinical consequences of drug-resistance to malaria and HIV treatment, the detection and surveillance of drug-resistance, and approaches to prevent development of drug-resistance.
  • Contrast the roles of prevention, diagnosis and treatment to control of HIV and malaria applied to specific epidemiological circumstances.
  • Critically analyse factors which determine policy for malaria and HIV control globally and nationally.
  • Recognise, select and appraise epidemiological and mathematical research methods used in the projection of communicable disease trends and the evaluation of individual and population effects of communicable disease interventions.

Sessions:

 

  1. Epidemiology and natural history of HIV: The global epidemic and local determinants
  2. Diagnosis and treatment of HIV
  3. Prevention of HIV
  4. Epidemiology and natural history of malaria: The global epidemic and local determinants
  5. Diagnosis and treatment of malaria
  6. Prevention of malaria
  7. Mathematical models applied to HIV and malaria: basic methods
  8. Vaccine development and the trials for HIV malaria

 

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