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Module leads

Brian Angus

Adrian Smith

Learning objectives

  • Describe the current epidemiological burden of HIV and malaria across the globe, and analyse the temporal, spatial and individual determinants of differences in epidemiology of both infections
  • Outline the natural history, pathogenicity and virulence of HIV and malaria in humans, and the routes and effectiveness of transmission of both infections.
  • Outline the basic principles of vaccine development, methods to assess the efficacy and population effectiveness of vaccines and summarise the prospects for vaccine-based prevention of HIV and malaria.
  • Compare and contrast approaches to the prevention of transmission of HIV and malaria, the empiric evidence quantifying the individual and population effect of prevention approaches.
  • Outline the methods of diagnosis of HIV and malaria, and their in the public health response.
  • Outline current therapies for malaria and HIV, their mechanisms of action and the empiric evidence of effectiveness of current approaches to treatment.
  • Outline the mechanisms and clinical consequences of drug-resistance to malaria and HIV treatment, the detection and surveillance of drug-resistance, and approaches to prevent development of drug-resistance.
  • Contrast the roles of prevention, diagnosis and treatment to control of HIV and malaria applied to specific epidemiological circumstances.
  • Critically analyse factors which determine policy for malaria and HIV control globally and nationally.
  • Recognise, select and appraise epidemiological and mathematical research methods used in the projection of communicable disease trends and the evaluation of individual and population effects of communicable disease interventions.



  1. Epidemiology and natural history of HIV: The global epidemic and local determinants
  2. Diagnosis and treatment of HIV
  3. Prevention of HIV
  4. Epidemiology and natural history of malaria: The global epidemic and local determinants
  5. Diagnosis and treatment of malaria
  6. Prevention of malaria
  7. Mathematical models applied to HIV and malaria: basic methods
  8. Vaccine development and the trials for HIV malaria