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Module leads

Jonathan Emberson Jonathan Emberson

Richard Haynes Richard Haynes

Learning objective:

  • To understand and explain the design, conduct and statistical analysis of clinical trials and meta-analyses
  • To be able to critically appraise publications (including protocols) related to these types of studies


  1. Large-scale randomised evidence
  2. Trial design 
  3. Trial conduct
  4. Statistical methods for the analysis of clinical trials
  5. Safety and sensible guidelines
  6. Systematic reviews: design and methods
  7. Meta-analysis: statistical methods
  8. Meta-analysis: interpreting evidence from randomised controlled trials
  9. Meta-analysis: interpreting evidence from observational studies
  10. Critical appraisal of systematic reviews