Large simple randomized controlled trials-from drugs to medical devices: lessons from recent experience.
Buccheri S. et al, (2025), Trials, 26
The potential for improving cardio-renal outcomes in chronic kidney disease with the aldosterone synthase inhibitor vicadrostat (BI 690517): a rationale for the EASi-KIDNEY trial.
Judge PK. et al, (2024), Nephrol Dial Transplant
Accelerating Evidence Generation: Addressing Critical Challenges and Charting a Path Forward
LANDRAY M., (2024), Journal of Clinical and Translational Science
Empagliflozin lowers serum uric acid in chronic kidney disease: exploratory analyses from the EMPA-KIDNEY trial.
Mayne KJ. et al, (2024), Nephrol Dial Transplant
Overcoming the barriers to better evidence generation from clinical trials
LANDRAY M., (2024), Trials
Relative Effectiveness of High-Dose vs. Standard-Dose Quadrivalent Influenza Vaccine in Older Adults with Cardiovascular Disease: A Prespecified Analysis of the DANFLU-1 Randomized Clinical Trial.
Christensen J. et al, (2024), Circ Cardiovasc Qual Outcomes
High-Dose vs Standard-Dose Influenza Vaccine in Chronic Kidney Disease: A Secondary Analysis of DANFLU-1.
Bartholdy KV. et al, (2024), J Am Coll Cardiol
Sodium-glucose co-transporter 2 inhibitors (SGLT2i) for hospitalised patients with COVID-19: prospective meta-analysis of randomised trials
LANDRAY M. et al, (2024), The Lancet Diabetes and Endocrinology
Frailty, multimorbidity and polypharmacy: exploratory analyses of the effects of empagliflozin from the EMPA-KIDNEY trial.
Mayne KJ. et al, (2024), Clin J Am Soc Nephrol, 19, 1119 - 1129
The Integration of Clinical Trials With the Practice of Medicine: Repairing a House Divided.
Angus DC. et al, (2024), JAMA
Effects of high-dose versus standard-dose quadrivalent influenza vaccine among patients with diabetes: A post-hoc analysis of the DANFLU-1 trial.
Lassen MCH. et al, (2024), Diabetes Obes Metab, 26, 1821 - 1829
Effects of statin therapy on diagnoses of new-onset diabetes and worsening glycaemia in large-scale randomised blinded statin trials: an individual participant data meta-analysis.
Cholesterol Treatment Trialists’ (CTT) Collaboration. Electronic address: ctt@ndph.ox.ac.uk None. and Cholesterol Treatment Trialists’ (CTT) Collaboration None., (2024), Lancet Diabetes Endocrinol, 12, 306 - 319
Framework of the Strengths and Challenges of Clinically Integrated Trials: An Expert Panel Report
Peters AE. et al, (2024), American Heart Journal
Immunomodulatory therapy in children with paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS, MIS-C; RECOVERY): a randomised, controlled, open-label, platform trial.
RECOVERY Collaborative Group None., (2024), Lancet Child Adolesc Health, 8, 190 - 200
Effects of Empagliflozin on Fluid Overload, Weight, and Blood Pressure in CKD.
Mayne KJ. et al, (2024), J Am Soc Nephrol, 35, 202 - 215