Yu-Jie Chiou
Colleges
Yu-Jie Chiou
MD, MSc
DPhil Student
Yu-Jie's research focusses on quantifying the genetic information and integration of epidemiological data in Alzheimer’s disease. He investigates how genetics, epidemiological data, particularly education, vascular risk factors, neuroimaging information interact in their effects on the odds of developing Alzheimer’s disease.
His research could be an effective avenue toward prioritising complicated mechanisms related to intervention of Alzheimer’s disease. Eventually, his research would translate the genetic and epidemiologic findings into drug targets. The big dataset of the major consortia investigating Alzheimer’s disease (European Alzheimer's Disease DNA BioBank (EADB) and Alzheimer's Disease Sequencing Project (ADSP)) as well as UK Biobank will be applied in his study.
Yu-Jie completed his Doctor of Medicine degree at Kaohsiung Medical University and MSc Health and Society: Social Epidemiology at University College London (Distinction), with the dissertation “Midlife physical activity on later-life cognition and brain health.” Prior to joining Oxford Population Health, he worked as a lecturer and attending physician specialising in psychiatry in Taiwan. His graduate study is fully funded by Kaohsiung Chang Gung Memorial Hospital Grant.
Recent publications
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Interplay of Metabolome and Gut Microbiome in Individuals With Major Depressive Disorder vs Control Individuals.
Journal article
Amin N. et al, (2023), JAMA Psychiatry, 80, 597 - 609
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Timing of physical activity across adulthood on later-life cognition: 30 years follow-up in the 1946 British birth cohort
Journal article
James S-N. et al, (2023), Journal of Neurology, Neurosurgery & Psychiatry
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Interplay of the human exposome, metabolome and gut microbiome in dementia and major depression
Conference paper
van Duijn CM. et al, (2022), Alzheimer's and Dementia, 18
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Morbidity and Associated Factors of Depressive Disorder in Patients With Parkinson's Disease
Journal article
Lee Y. et al, (2022), Journal of Nervous & Mental Disease, 210, 777 - 783
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Longitudinal analysis of UK Biobank participants suggests age and APOE-dependent alterations of energy metabolism in development of dementia
Preprint
Liu J. et al, (2022)
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A dyadic study of psychological well-being of individuals with Parkinson’s disease and their caregivers
Journal article
Lee Y. et al, (2021), Scientific Reports, 11
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Association between paternal age and risk of schizophrenia: a nationwide population–based study
Journal article
Lan K. et al, (2020), Journal of Assisted Reproduction and Genetics
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Prevalence and Associated Factors of Depressive Disorder in Caregivers of Individuals With Parkinson Disease
Journal article
Lee Y. et al, (2020), Journal of Geriatric Psychiatry and Neurology, 0891988720933359 - 0891988720933359
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Brain-derived neurotrophic factor (BDNF) and bipolar disorder
Journal article
Chiou Y. and Huang T., (2019), Psychiatry Research, 274, 395 - 399
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Accuracy of brain-derived neurotrophic factor levels for differentiating between Taiwanese patients with major depressive disorder or schizophrenia and healthy controls
Other
Chiou Y. and Huang T., (2019), PLoS One, 14