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The body ‘remembers’ inflammation, potentially increasing the risk of age-related disease later in life

Study finds blood stem cells retain ‘inflammatory memory’, shaping ageing, recovery, and disease risk, offering new insight into long‑term health.

Open-source toolkit enables discovery research within trusted research environments

Phenofhy, a new open‑source tool for streamlined phenotypic data processing and exploratory TRE work, has now launched to support biomedical discovery.

Opioid addiction linked to increased risk of dementia

Major study finds opioid addiction raises dementia risk by 56% compared with non‑users.

Research Topics

Aspirin and other anti-platelet drugs

We brought together all trials of antiplatelet drugs to show how treatments like aspirin reduce major vascular risks and to provide clinicians with reliable evidence.

Dementia and other neurodegenerative diseases

Our research focuses on the role of vascular risk factors in dementia and on the methodology of assessing cognitive status in very large-scale studies.

Diet, nutrition and obesity

We investigate how obesity, diet, and nutrition affect health and healthcare systems, and have investigated population-level interventions to promote healthier eating.

Death in old age is inevitable, but death before old age is not.

Sir Richard Doll CH OBE FRS (1912 - 2005)