Yu-Jie Chiou
Colleges
Yu-Jie Chiou
MD, MSc
DPhil Student
Yu-Jie's research focusses on quantifying the genetic information and integration of epidemiological data in Alzheimer’s disease. He investigates how genetics, epidemiological data, particularly education, vascular risk factors, neuroimaging information interact in their effects on the odds of developing Alzheimer’s disease.
His research could be an effective avenue toward prioritising complicated mechanisms related to intervention of Alzheimer’s disease. Eventually, his research would translate the genetic and epidemiologic findings into drug targets. The big dataset of the major consortia investigating Alzheimer’s disease (European Alzheimer's Disease DNA BioBank (EADB) and Alzheimer's Disease Sequencing Project (ADSP)) as well as UK Biobank will be applied in his study.
Yu-Jie completed his Doctor of Medicine degree at Kaohsiung Medical University and MSc Health and Society: Social Epidemiology at University College London (Distinction), with the dissertation “Midlife physical activity on later-life cognition and brain health.” Prior to joining Oxford Population Health, he worked as a lecturer and attending physician specialising in psychiatry in Taiwan. His graduate study is fully funded by Kaohsiung Chang Gung Memorial Hospital Grant.
Recent publications
Interplay between age, APOE Ɛ4 and the metabolome in plasma and brain in Alzheimer's disease.
Journal article
Amin N. et al, (2025), Transl Psychiatry, 15
The relationship between leisure time physical activity patterns, Alzheimer's disease markers and cognition.
Journal article
James S-N. et al, (2025), Brain Commun, 7
Interplay of Metabolome and Gut Microbiome in Individuals With Major Depressive Disorder vs Control Individuals.
Journal article
Amin N. et al, (2023), JAMA Psychiatry, 80, 597 - 609
Timing of physical activity across adulthood on later-life cognition: 30 years follow-up in the 1946 British birth cohort.
Journal article
James S-N. et al, (2023), J Neurol Neurosurg Psychiatry, 94, 349 - 356
Interplay of the human exposome, metabolome and gut microbiome in dementia and major depression
Conference paper
van Duijn CM. et al, (2022), Alzheimer's and Dementia, 18
Morbidity and Associated Factors of Depressive Disorder in Patients With Parkinson's Disease.
Journal article
Lee Y. et al, (2022), J Nerv Ment Dis, 210, 777 - 783
Prevalence and Risk Factors of Depression between Patients with Parkinson's Disease and Their Caregivers: A One-Year Prospective Study.
Journal article
Lee Y. et al, (2022), Healthcare (Basel), 10
Prevalence and Associated Factors of Depressive Disorder in Caregivers of Individuals With Parkinson Disease.
Journal article
Lee Y. et al, (2021), J Geriatr Psychiatry Neurol, 34, 418 - 425
