Dr Michael lay
Contact information
Michael Lay
Head of Project Information Science
- Information Security Coordinator and Information Governance Lead
Michael’s role encompasses strategic oversight over a number of programming and bioinformatics initiatives with Oxford Population Health, as well as responsibility for Information Security and Governance.
Michael directs and supervises a large team of programmers working on a number of large scale projects, particularly UK Biobank, HPS3/TIMI55-REVEAL and ASCEND, but also a number of other large-scale clinical trials. He also manages the Information Governance team within Oxford Population Health which handles initiatives including the NHS Information Governance Toolkit and ISO 27000.
Michael takes the direct programming lead on a number of bioinformatics initiatives, particularly with respect to the use of registry data and other resources to enhance and streamline clinical trials.
Prior to joining the Clinical Trial Service Unit & Epidemiological Studies Unit (CTSU) in 1996, Michael graduated with a double first class Physics degree from Brasenose College in Oxford and subsequently obtained a doctorate from Oxford for his work on the Sudbury Neutrino Observatory; the leader of the project was awarded Nobel prize for physics (2015).
During this period he also held a junior teaching fellowship at Corpus Christi College, Oxford, and moved on to work as a post-doctoral researcher in Oxford, continuing his work on computer simulations of the observatory.
Recent publications
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Effects of Aspirin for Primary Prevention in Persons with Diabetes Mellitus.
Journal article
ASCEND Study Collaborative Group None. et al, (2018), N Engl J Med, 379, 1529 - 1539
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Effects of n-3 Fatty Acid Supplements in Diabetes Mellitus.
Journal article
ASCEND Study Collaborative Group None. et al, (2018), N Engl J Med, 379, 1540 - 1550
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Effects of Vitamin D on Blood Pressure, Arterial Stiffness, and Cardiac Function in Older People After 1 Year: BEST-D (Biochemical Efficacy and Safety Trial of Vitamin D).
Journal article
Tomson J. et al, (2017), J Am Heart Assoc, 6
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Optimum dose of vitamin D for disease prevention in older people: BEST-D trial of vitamin D in primary care.
Journal article
Hin H. et al, (2017), Osteoporos Int, 28, 841 - 851
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Cost-effective recruitment methods for a large randomised trial in people with diabetes: A Study of Cardiovascular Events iN Diabetes (ASCEND).
Journal article
Aung T. et al, (2016), Trials, 17