Publications

Dengue, a mosquito-borne viral disease, is experiencing its largest surge in history, driven by climate and demographic change. Expanding transmission has highlighted previously under-recognised populations at heightened risk of severe disease, including people with multimorbidity and immunosuppression, for whom live-attenuated vaccines are contraindicated or unlicensed. This evolving epidemiology underscores the urgent need for safe and effective treatments for dengue, particularly for those with complex risk profiles compounded by socio-economic disadvantage. We examine ethical, regulatory, and implementation considerations to support World Health Organization target product profile development for dengue therapeutics. Our analysis highlights the need for better characterisation of risk groups, including through enhanced surveillance; co-produced approaches for their inclusion in research prioritisation, trials, and care; and strategies to address key barriers to access for all, such as rapid diagnostics. This framework has the potential to inform equitable development and delivery of countermeasures for other infectious threats to global health.

Johnson T. et al, (2026), The Lancet Microbe

WHO Target Product Profiles for Dengue Therapeutics: An Interdisciplinary Analysis of Ethical, Regulatory, and Implementation Considerations

Johnson T. et al, (2026), The Lancet Microbe

Hantavirus at sea: a test of the revised IHR and global health solidarity

Abdool Karim S. and Johnson T., (2026), The Lancet Global Health

Ethics of Antibiotic Course Duration: Shorter is Better.

Johnson T. et al, (2026), Am J Bioeth, 1 - 15

The role of microbial genomics in delivering the UK's national action plan for confronting antimicrobial resistance 2024-29.

Johnson T. et al, (2026), Lancet Microbe

Beyond Good and Bad: Rethinking Solidarity and Coercion in Public Health.

Johnson T. et al, (2026), Am J Bioeth, 1 - 14

The role of genomics in delivering the United Kingdom’s national action plan for confronting antimicrobial resistance 2024 to 2029

Johnson T. et al, (2026), The Lancet Microbe

Coercing for public health: (when) is coercion ethically justified?

Johnson T. et al, (2025), Monash Bioeth Rev, 43, 225 - 228

Coercive public health policies need context-specific ethical justifications.

Johnson T. et al, (2025), Monash Bioeth Rev, 43, 350 - 371

Coercing for public health: reflections on the role of coercion in public health emergencies.

Abdool Karim S. et al, (2025), Monash Bioeth Rev, 43, 384 - 397

Ethics of Identifying Individuals Involved in HIV Transmission Events by Phylogenetics in Molecular Surveillance.

Faber F. et al, (2025), Bioethics, 39, 762 - 771

A just war on bugs? Ethical differences between antimalarial resistance and antibacterial resistance.

Johnson T. et al, (2025), BMJ Glob Health, 10

Clinical metagenomics: ethical issues.

Johnson T. et al, (2025), J Med Microbiol, 74

A Just Transition for Antimicrobial Resistance: The Need for More Forms and a Broader Scope of Justice.

Tegama N. et al, (2025), Public Humanit, 1

Recognizing the ethical complexity of food policies and the role of the food industry.

Abdool Karim S. et al, (2024), Health Promot Int, 39

Search results (43)

WHO Target Product Profiles for Dengue Therapeutics: An Interdisciplinary Analysis of Ethical, Regulatory, and Implementation Considerations

Hantavirus at sea: a test of the revised IHR and global health solidarity

Ethics of Antibiotic Course Duration: Shorter is Better.

The role of microbial genomics in delivering the UK's national action plan for confronting antimicrobial resistance 2024-29.

Beyond Good and Bad: Rethinking Solidarity and Coercion in Public Health.

The role of genomics in delivering the United Kingdom’s national action plan for confronting antimicrobial resistance 2024 to 2029

Coercing for public health: (when) is coercion ethically justified?

Coercive public health policies need context-specific ethical justifications.

Coercing for public health: reflections on the role of coercion in public health emergencies.

Ethics of Identifying Individuals Involved in HIV Transmission Events by Phylogenetics in Molecular Surveillance.

A just war on bugs? Ethical differences between antimalarial resistance and antibacterial resistance.

Clinical metagenomics: ethical issues.

A Just Transition for Antimicrobial Resistance: The Need for More Forms and a Broader Scope of Justice.

Recognizing the ethical complexity of food policies and the role of the food industry.

Leading Human Health Forward

Cookies on this website

Search results (43)

Leading Human Health Forward