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We describe detection in the United Kingdom (UK) of the drug-resistant Neisseria gonorrhoeae FC428 clone, with ceftriaxone resistance and intermediate azithromycin resistance. Two female patients developed infection following contact with UK-resident men from the same sexual network linked to travel to Ibiza, Spain. One case failed treatment with ceftriaxone, and azithromycin and gentamicin, before successful treatment with ertapenem. Both isolates had indistinguishable whole-genome sequences. Urgent action is essential to contain this drug-resistant strain.

Original publication

DOI

10.2807/1560-7917.ES.2019.24.10.1900147

Type

Journal article

Journal

Euro Surveill

Publication Date

03/2019

Volume

24

Keywords

antimicrobial resistance, antimicrobial treatment, gonorrhoeae, treatment failure, whole-genome sequencing