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The rapid and continuing progress in gene discovery for complex diseases is fueling interest in the potential application of genetic risk models for clinical and public health practice. The number of studies assessing the predictive ability is steadily increasing, but the quality and completeness of reporting varies. A multidisciplinary workshop sponsored by the Human Genome Epidemiology Network developed a checklist of 25 items recommended for strengthening the reporting of Genetic RIsk Prediction Studies (GRIPS), building on the principles established by prior reporting guidelines. These recommendations aim to enhance the transparency of study reporting, and thereby to improve the synthesis and application of information from multiple studies that might differ in design, conduct, or analysis. A detailed Explanation and Elaboration document is published.

Original publication

DOI

10.1007/s10654-011-9552-y

Type

Journal article

Journal

Eur J Epidemiol

Publication Date

04/2011

Volume

26

Pages

255 - 259

Keywords

Disclosure, Education, Epidemiologic Studies, Genetic Predisposition to Disease, Genetic Testing, Guidelines as Topic, Humans, Interdisciplinary Communication, Risk Assessment