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We present the case of a 77-year-old woman who initially presented with pyrexia of unknown origin, anaemia and mild renal impairment. When her omeprazole was stopped she improved rapidly. When omeprazole was re-started she developed fever and acute renal failure, which again settled quickly on discontinuation of omeprazole. This case demonstrates how drugs can cause severe multisystem disorders that may appear to be infective or inflammatory.


Journal article


Postgrad Med J

Publication Date





416 - 418


Acute Kidney Injury, Aged, Anemia, Anti-Inflammatory Agents, Anti-Ulcer Agents, Blood Sedimentation, Dyspepsia, Female, Fever, Humans, Omeprazole, Prednisolone, Recurrence