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Endometrial cancer is the fourth most common female cancer in the UK and the most common gynaecological cancer. Quality of life and symptom control needs to be considered in women who enter a surgically induced menopause. Hormone replacement in this population has been controversial to date. The current evidence regarding the safety of estrogen only and combined hormone replacement therapy is discussed in this review. The use of topical vaginal therapies, alternate therapies and the current data regarding testosterone use for symptom control is also outlined.

Original publication




Journal article


Menopause Int

Publication Date





134 - 138


Androgens, Endometrial Neoplasms, Estrogen Replacement Therapy, Estrogens, Female, Hormone Replacement Therapy, Humans, Menopause, Premature, Testosterone, Vaginal Creams, Foams, and Jellies