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As in many areas of health care, treatments for cancer may differ only moderately in their effects on major end points, such as death. But, such differences are worth knowing about, particularly in common diseases in which they could represent a substantial benefit to public health. Large-scale randomized evidence allows moderate differences to be investigated reliably, and one way to achieve this is by meta-analyses of updated and centrally collected individual patient data from all relevant trials. This paper illustrates why this form of research can often be important in cancer. It also offers the first list of such projects, as a source of information on current and past research in this area.

Type

Journal article

Journal

Br J Cancer

Publication Date

06/1998

Volume

77

Pages

2036 - 2044

Keywords

Humans, Meta-Analysis as Topic, Neoplasms, Randomized Controlled Trials as Topic