Cookies on this website
We use cookies to ensure that we give you the best experience on our website. If you click 'Continue' we'll assume that you are happy to receive all cookies and you won't see this message again. Click 'Find out more' for information on how to change your cookie settings.

A serosurvey was conducted in a random sample of 259 women and 231 men in 12 rural communities in Mwanza Region, Tanzania, using a type-specific ELISA for Herpes simplex virus type 2 (HSV-2) infection. Seroprevalence rose steeply with age to approximately 75% in women >=25 years old and 60% in men >=30. After adjusting for age and residence, HSV-2 prevalence was higher in women who were married, in a polygamous marriage, Treponema pallidum hemagglutination assay (TPHA)-positive, had more lifetime sex partners, or who had not traveled. Prevalence was higher in men who were married, had lived elsewhere, had more lifetime partners, had used condoms, or were TPHA-positive. HSV-2 infection was significantly associated with recent history of genital ulcer. The association between HSV-2 infection and lifetime sex partners was strongest in those <25 years old in both sexes. This association supports the use of HSV-2 serology as a marker of risk behavior in this population, particularly among young people.

Original publication

DOI

10.1086/314555

Type

Conference paper

Publication Date

01/1999

Volume

179

Pages

16 - 24

Keywords

Adolescent, Adult, Age Factors, Antibodies, Bacterial, Antibodies, Viral, Biomarkers, Enzyme-Linked Immunosorbent Assay, Female, Herpes Genitalis, Herpesvirus 2, Human, Humans, Male, Marriage, Middle Aged, Risk-Taking, Rural Population, Seroepidemiologic Studies, Sexual Behavior, Sexual Partners, Tanzania, Treponema pallidum