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Over the past year, a heated discussion about 'circular' or 'nonindependent' analysis in brain imaging has emerged in the literature. An analysis is circular (or nonindependent) if it is based on data that were selected for showing the effect of interest or a related effect. The authors of this paper are researchers who have contributed to the discussion and span a range of viewpoints. To clarify points of agreement and disagreement in the community, we collaboratively assembled a series of questions on circularity herein, to which we provide our individual current answers in <or=100 words per question. Although divergent views remain on some of the questions, there is also a substantial convergence of opinion, which we have summarized in a consensus box. The box provides the best current answers that the five authors could agree upon.

Original publication

DOI

10.1038/jcbfm.2010.86

Type

Journal article

Journal

J Cereb Blood Flow Metab

Publication Date

09/2010

Volume

30

Pages

1551 - 1557

Keywords

Brain, Brain Mapping, Data Interpretation, Statistical, Guidelines as Topic, Image Processing, Computer-Assisted, Neurosciences, Publications, Research Design, Selection Bias