Secondhand smoke exposure is independently associated with stroke among non-smoking adults in West Africa.
Okekunle AP., Asowata OJ., Fakunle AG., Akpa OM., Sarfo FS., Akpalu A., Wahab K., Obiako R., Komolafe M., Owolabi L., Osaigbovo GO., Tiwari HK., Akinyemi J., Jenkins C., Arulogun O., Ibinaiye P., Appiah L., Agunloye AM., Adeoye AM., Yaria J., Calys-Tagoe B., Uvere EO., Ogbole G., Agyekum F., Sanni TA., Amusa GA., Ogunronbi M., Olowookere S., Balogun O., Ogunmodede JA., Olalusi OV., Samuel D., Mande A., Rabiu M., Adebayo P., Sunday A., Imoh LC., Oguntade AS., Ajose A., Singh A., Adeegbe OT., Mensah Y., Fawale MB., Abdul S., Ikubor J., Tolulope A., Yahaya IS., Akisanya C., Odo CJ., Efidi R., Chukwuonye II., Shidali V., Adebowale A., Ohagwu KA., Adeleye OO., Iheonye H., Akintunde A., Olabinri E., Akpalu J., Adesina J., Onyeonoro U., Onasanya A., Arnett DK., Lackland D., Akinyemi R., Ovbiagele B., Owolabi M., SIREN .
BACKGROUND: Stroke is a leading cause of disability and mortality worldwide, but little is known about the contribution of secondhand smoke exposure (SHSE) to stroke epidemiology among indigenous Africans. OBJECTIVE: To evaluate the association of SHSE with stroke among indigenous Africans. METHODS: We analyzed the relationship of SHSE with stroke among 2990 case-control pairs of adults who had never smoked (identified in the SIREN study) using conditional logistic regression at a two-sided P < 0.05. RESULTS: Multivariable-adjusted odds ratio and 95% confidence interval; 1.25 (1.04, 1.50; P = 0.02) revealed SHSE was positively associated with stroke independent of stroke subtypes. CONCLUSION: Culturally relevant primary prevention strategies targeted at SHSE might be promising in preventing stroke among Africans.