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A large epidemiological data set was used to identify 115 patients who died from a cardiovascular cause within 30 days of elective surgery under general anaesthesia. For each patient, a control was identified, matched for age (within 5 yr of the patient), sex, operation and consultant. Patients and controls were compared for cardiovascular risk factors in a matched analysis using conditional logistic regression, and a prognostic model was generated. Three risk factors were included in the final model: previous myocardial infarction (odds ratio 3.18 (95% confidence intervals (CI) 1.22-8.28), P = 0.018), history of hypertension (odds ratio 1.90 (0.99-3.62), P = 0.047) and renal failure (odds ratio 3.56 (1.04-12.10), P = 0.043).

Original publication

DOI

10.1093/bja/80.1.14

Type

Journal article

Journal

British journal of anaesthesia

Publication Date

01/1998

Volume

80

Pages

14 - 19

Addresses

Nuffield Department of Anaesthetics, John Radcliffe Hospital, Oxford.

Keywords

Humans, Cardiovascular Diseases, Myocardial Infarction, Hypertension, Anesthesia, General, Logistic Models, Risk Factors, Case-Control Studies, Adult, Aged, Aged, 80 and over, Middle Aged, England, Female, Male, Renal Insufficiency, Elective Surgical Procedures