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Professor Sasha Shepperd

Professor Sasha Shepperd

Contact information

Email
sasha.shepperd@ndph.ox.ac.uk

Research groups

Applied Health Research Unit (AHRU)

Websites

Ethnicity and breast cancer
Funded by the Prevention and Population Research Committee at Cancer Research UK (CI Toral Gathani)
Old Age Neuroscience and the ORCHARD portfolio
Nuffield Department of Clinical Neurosciences

Sasha Shepperd

BA, MSc, DPhil

Professor of Health Services Research & Interim Director of HERC

Co-lead of the Applied Health Research Unit
Oxford Population Health lead for equality, diversity and inclusion

Sasha’s research uses epidemiological methods, randomised trials and evidence synthesis to answer pressing health service/systems questions, with a focus on population ageing. Sasha was the chief investigator of a NIHR funded multi-site randomised trial of Hospital at Home vs hospital admission that was awarded the BGS Dhole-Eddlestone Memorial prize in 2023 and contributed to the evidence supporting NHS England’s virtual ward programme. Currently her research includes understanding the impact of inequalities that drive the need for social care by an older population, she is a co-investigator on CRUK funded research (led by Toral Gathani) on barriers and facilitators to the early diagnosis of breast cancer in ethnic minority women and a co-lead for the Cochrane Thematic Group: People, Health Systems and Public Health.

After an undergraduate degree in psychology from the University of Vermont, Sasha completed a master's at the Harvard School of Public Health and a DPhil at the University of Oxford.

Key publications

FedExIT - Missing Class-agnostic Semi-Supervised Federated Learning with Extreme Imbalance Tackling Scheme

Saha P. et al, (2026), Information Fusion, 130, 104080 - 104080

Perceptions of death, dying and the body in Vietnamese culture: A qualitative exploration from a study examining the potentials of minimally invasive tissue sampling in Vietnam

Doan NP. et al, (2026), Ssm Qualitative Research in Health, 9

Trends in pneumothorax mortality in England (2004-2023): a population-based observational study.

Zhong X. et al, (2026), Lancet Reg Health Eur, 64

Clustering of cardiovascular risk factors and their association with socio-demographic and lifestyle factors in middle-aged and older adults in rural northeast South Africa: Findings from HAALSI

Mhembere MN. et al, (2026), Public Health, 254, 106246 - 106246

Stroke in China: advances in prevention and management on the path to a healthy China.

Wu S. et al, (2026), Lancet Neurol, 25, 379 - 395

Measuring and decomposing income inequalities in child and adolescent mental health in the UK

Yang M. et al, (2026), European Journal of Health Economics

Harmonised Health Outcomes Across Administrative Data: Lessons, Opportunities, and Challenges from UK Biobank

Domzaridou E. et al, (2026)

Proton beam therapy for oropharyngeal cancer (TORPEdO): a phase 3, randomised controlled trial.

Thomson DJ. et al, (2026), Lancet

Effect of thiazolidinediones compared to other antidiabetic medications on incident dementia in people with type 2 diabetes: A target trial emulation study

Offorha BCC. et al, (2026)

Liquid biopsy for the diagnosis of EBV-positive Burkitt's lymphoma in endemic areas.

Chamba C. et al, (2026), Nat Med

Cohort and Data Resource Update: Mexico City Prospective Study

EMBERSON J. et al, (2026), BMJ Medicine

A clinician's guide to probabilistic suicide risk prediction tools.

Webb J. and Fazel S., (2026), Br J Psychiatry, 1 - 2

Identifying common mental disorders among perinatal and non-perinatal women in northern India: a cross-sectional validation study of the diagnostic accuracy of six self-report measures.

Fellmeth G. et al, (2026), BMJ Open, 16

Dynamic Count Models with Flexible Innovation Processes for Irregular Maritime Migration

Zens G. and Bijak J., (2026), Annals of Applied Statistics

Short-term effects of temperature on physical activity and sedentary behavior in Chinese adults: An accelerometer-based analysis.

Wei L. et al, (2026), Environ Int, 210

Lifetime Effects of Adherence to Cardiovascular and Diabetes Medications in Spain: A Modelling Study in a Population Cohort of 152,117 Patients.

Sánchez-Viñas A. et al, (2026), Pharmacoeconomics

Safety and personalised care in maternity services of England for women whose preferred language is not English: A critical race theory analysis of interpreter experiences

Baz S. et al, (2026), BMJ Public Health

Development and validation of an ECG-based 10-year risk prediction model for Major Adverse Cardiac and Cerebrovascular Events in UK Biobank

Sturge A. et al, (2026)

Primer on Large-Sample Statistical Inference for Epidemiologists

Shook-Sa B. et al, (2026), Epidemiologic Methods

The Rogan-Gladen estimator for outcome misclassification

Edwards J. et al, (2026), American Journal of Epidemiology

Primer on Large-Sample Statistical Inference for Epidemiologists

Shook-Sa B. et al, (2026), Epidemiologic Methods

‘Readiness’ as a model to explain the differing adoption rates of gene editing technology in the laboratory and industrial manufacturing sites

Morrison M. and Bartlett A., (2026), Innovation: The European Journal of Social Science Research, 1 - 22

Basal metabolic rate and risk for diabetes and its complications among 341,790 adults from the UK Biobank.

Frimpong J. et al, (2026), Diabetes Res Clin Pract, 235

Sleep and circadian health in the UK Biobank: Report on the 2023 sleep questionnaire enhancement.

Tse KYK. et al, (2026), Sleep

Ethics of Antibiotic Course Duration: Shorter is Better.

Johnson T. et al, (2026), Am J Bioeth, 1 - 15

Schistosoma mansoni infections are associated with hepatosplenic organometry within the context of repeated praziquantel treatment and co-endemic infections of malaria, hepatitis B, and HIV: a population-based study in rural Uganda

Seggelke K. et al, (2026)

Associations of 6600 SomaScan proteins with demographic, lifestyle, environmental and health characteristics in Chinese adults

CHEN Z. et al, (2026), Scientific Reports

Change in early respiratory management of infants born at less than 30 weeks' gestation in England and Wales: an observational cohort study.

Farley H. et al, (2026), Arch Dis Child Fetal Neonatal Ed

Causes of excess non-lymphoma death in 58,000 patients with DLBCL diagnosed during 1997-2020 and followed for up to 25 years.

Challenger A. et al, (2026), Blood Adv

The role of microbial genomics in delivering the UK's national action plan for confronting antimicrobial resistance 2024-29.

Johnson T. et al, (2026), Lancet Microbe

Interplay of Age and Sex With Clinic and Ambulatory Blood Pressure and Mortality.

Böhm M. et al, (2026), Hypertension

Producing Value or Responding to Valuation?

Morrison M. and Bicudo E., (2026), Science & Technology Studies

In the wake of USAID cuts, we can create a Demographic and Health Survey Program founded on more equitable data infrastructure and stronger research integrity.

Abdel Ghany J. et al, (2026), Proc Natl Acad Sci U S A, 123

Bayesian machine learning enables discovery of risk factors for hepatosplenic multimorbidity related to schistosomiasis.

Zhi Y-C. et al, (2026), Nat Commun

Schistosoma mansoni infections are associated with faecal calprotectin markers of gut inflammation after accounting for HIV, hepatitis B, and malaria

Wilburn L. et al, (2026), Journal of Infectious Diseases

A Life Identification Number Barcoding (LIN Code) System for Neisseria meningitidis: high resolution multi-level typing of meningococci.

Parfitt KM. et al, (2026)

Female Reproductive Cancers and the Sex Gap in Survival.

Canudas-Romo V. et al, (2026), JAMA Netw Open, 9

Phenome-Wide Associations of Polygenic Scores for Schizophrenia and Major Depression in 100,000 Chinese Adults.

Wang B. et al, (2026), Biol Psychiatry Glob Open Sci, 6

A national audit of 1724 post-colonoscopy colorectal cancers: understanding causes and consequences.

Burr N. et al, (2026), Endoscopy, 58, 251 - 261

Economic Evaluations of Medication Safety Interventions in Primary and Long-Term Care: A Systematic Review.

Amritlal ST. et al, (2026), Pharmacoeconomics, 44, 299 - 316

A national audit of 1724 post-colonoscopy colorectal cancers: understanding causes and consequences.

Burr N. et al, (2026), Endoscopy, 58, 251 - 261

Economic Evaluations of Medication Safety Interventions in Primary and Long-Term Care: A Systematic Review.

Amritlal ST. et al, (2026), Pharmacoeconomics, 44, 299 - 316

Linking human and planetary health: focus on environmental sustainability and health care

Jecker NS. et al, (2026), Environmental Research Health, 4

Lessons from developing the Papua New Guinea National Health Research Agenda 2025–2030

Dindi M. et al, (2026), The Lancet Regional Health - Western Pacific, 68, 101830 - 101830

Towards an ethics of vigilance in public health

Webb J., (2026), JME Practical Bioethics, 2, e000074 - e000074

Vegetarian diets and cancer risk: pooled analysis of 1.8 million women and men in nine prospective studies on three continents.

Dunneram Y. et al, (2026), Br J Cancer

Factors associated with adherence to allocated treatment in the ASCEND trial: a mail-based randomised trial of aspirin and of omega-3 fatty acid supplementation in people with diabetes.

Madurasinghe VW. et al, (2026), Trials, 27

Beyond Good and Bad: Rethinking Solidarity and Coercion in Public Health.

Johnson T. et al, (2026), Am J Bioeth, 1 - 14

Association Between 24-Hour Systolic Blood Pressure Time in Target Range and Mortality.

Lauder L. et al, (2026), Hypertension

Impact of sleep habits on life expectancy free of cardiovascular disease in the Chinese population: a prospective cohort study.

Sun Q. et al, (2026), J Gerontol A Biol Sci Med Sci

Temporary Shock or Lasting Scar? Life Expectancy Trajectories Since COVID-19

Dowd JB. et al, (2026)

Genetic substructure in Latin American individuals reveals novel associations, mechanistic insights, and variable polygenic risk score transferability for alcohol traits

Montalvo-Ortiz J. et al, (2026)

Young adulthood adiposity in relation to all-cause and cause-specific mortality: a prospective study of 0.5 million Chinese adults.

Fan L. et al, (2026), Sci Bull (Beijing)

Cause-specific excess mortality in rural India during the COVID-19 pandemic 2020-2023: longitudinal analyses of deaths in 0.2 million rural health facilities.

Kumar P. et al, (2026), BMJ Open, 16

Cannabis use, cognitive function and dementia risk in older adults: observational and genetic analyses.

Ishrat S. et al, (2026), BMJ Ment Health, 29

Opportunities, Challenges, and Validation Strategies to Advance Cardiovascular Research Using Population Cohorts.

Salih AM. et al, (2026), JAMA Cardiol

Rare coding variants in CHRNB3 associate with reduced daily cigarette smoking across ancestries.

Rajagopal VM. et al, (2026), Nat Commun, 17

Substantial international variation in the cost of blood group and save and crossmatch: A systematic review.

Fabiano G. et al, (2026), Br J Haematol

Temperature and sex ratios at birth.

Abdel Ghany J. et al, (2026), Proc Natl Acad Sci U S A, 123

Towards a Multi-sectoral Approach to Population Health: A Scoping Review of Cross-sectoral Evaluations of Health Interventions.

Koleva-Kolarova R. et al, (2026), Appl Health Econ Health Policy

Recent publications

Proactive Integrated Consultation-Liaison Psychiatry for older medical inpatients: The HOME Study RCT of its effectiveness and cost-effectiveness.

Sharpe M. et al, (2025), Health Soc Care Deliv Res, 13, 1 - 85

Prevalence of cognitive morbidity including delirium in 51,202 emergency hospital admissions across 29 medical and surgical specialties in ORCHARD-EPR: a cross-sectional study.

Boucher EL. et al, (2025), EClinicalMedicine, 90

Temporal trends in hospital-recorded pulmonary embolism in England before, during and after the COVID-19 pandemic (2008-2024): a population-based observational study.

Zhong X. et al, (2025), Lancet Reg Health Eur, 58

Social inequalities in the use of formal and informal home care in older women: evidence from a large UK cohort study.

Quinn M. et al, (2025), Age Ageing, 54

Trends and variation in the incidence of hip fracture in England before, during, and after the COVID-19 pandemic (2014-2024): a population-based observational study.

Webster J. et al, (2025), Lancet Reg Health Eur, 57

Delirium prevalence, diagnostic uncertainty and outcomes in ORCHARD-EPR: validation against prospective reference cohorts.

Boucher EL. et al, (2025), Age Ageing, 54

Implementation of Delirium Screening at Scale in Older Patients With Emergency Hospital Admission.

Boucher EL. et al, (2025), JAMA Intern Med, 185, 884 - 887

Cancer inequalities in the United Kingdom and the data used to measure them: a scoping review.

Underwood S. et al, (2025), Lancet Reg Health Eur, 52

Factors that influence recruitment to COVID-19 vaccine trials: a qualitative evidence synthesis.

Biesty L. et al, (2024), Trials, 25

Barriers to and enablers of the early diagnosis of breast cancer among women from ethnic minority backgrounds in the UK: protocol for a qualitative evidence synthesis.

Sajjad P. et al, (2024), BMJ Open, 14

More publications