Michael Holmes

• Association of Body Mass Index With Cardiometabolic Disease in the UK Biobank: A Mendelian Randomization Study.

  Lyall DM. et al, (2017), JAMA Cardiol

• Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study.

  Zewinger S. et al, (2017), Lancet Diabetes Endocrinol, 5, 534 - 543

• Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus: A Mendelian Randomization Analysis.

  Dale CE. et al, (2017), Circulation, 135, 2373 - 2388

• Mendelian randomisation in cardiovascular research: an introduction for clinicians.

  Bennett DA. and Holmes MV., (2017), Heart

• Mendelian randomization in cardiometabolic disease: challenges in evaluating causality.

  Holmes MV. et al, (2017), Nat Rev Cardiol

• Genetic variants associated with type 2 diabetes and adiposity and risk of intracranial and abdominal aortic aneurysms.

  van 't Hof FN. et al, (2017), Eur J Hum Genet, 25, 758 - 762

• Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study

  Zewinger S. et al, (2017), Lancet Diabetes and Endocrinology

• Diabetes, plasma glucose and incidence of pancreatic cancer: A prospective study of 0.5 million Chinese adults and a meta-analysis of 22 cohort studies.

  Pang Y. et al, (2017), Int J Cancer, 140, 1781 - 1788

• PCSK9 genetic variants and risk of type 2 diabetes: a mendelian randomisation study.

  Schmidt AF. et al, (2017), Lancet Diabetes Endocrinol, 5, 97 - 105

• Cannabis use and risk of schizophrenia: a Mendelian randomization study.

  Vaucher J. et al, (2017), Mol Psychiatry

• Association Between Diabetes and Cause-Specific Mortality in Rural and Urban Areas of China.

  Bragg F. et al, (2017), JAMA, 317, 280 - 289

• The Relationship between Body Mass Index and 10-Year Trajectories of Physical Functioning in Middle-Aged and Older Russians: Prospective Results of the Russian HAPIEE Study.

  Hu Y. et al, (2017), J Nutr Health Aging, 21, 381 - 388

• Commentary: Mendelian randomization-inspired causal inference in the absence of genetic data.

  Zuccolo L. and Holmes MV., (2016), Int J Epidemiol

• Adult height, coronary heart disease and stroke: a multi-locus Mendelian randomization meta-analysis.

  Nüesch E. et al, (2016), Int J Epidemiol, 45, 1927 - 1937

• Genetic analysis of emerging risk factors in coronary artery disease.

  van Iperen EP. et al, (2016), Atherosclerosis, 254, 35 - 41

• Long-Term Survival and Freedom From Reintervention After Off-Pump Coronary Artery Bypass Grafting: A Propensity-Matched Study.

  Kirmani BH. et al, (2016), Circulation, 134, 1209 - 1220

• Selecting instruments for Mendelian randomization in the wake of genome-wide association studies.

  Swerdlow DI. et al, (2016), Int J Epidemiol, 45, 1600 - 1616

• Association of Lipid Fractions With Risks for Coronary Artery Disease and Diabetes.

  White J. et al, (2016), JAMA Cardiol, 1, 692 - 699

• Cystatin C and Cardiovascular Disease: A Mendelian Randomization Study.

  van der Laan SW. et al, (2016), J Am Coll Cardiol, 68, 934 - 945

• Evaluation of type 2 diabetes genetic risk variants in Chinese adults: findings from 93,000 individuals from the China Kadoorie Biobank.

  Gan W. et al, (2016), Diabetologia, 59, 1446 - 1457

• Harnessing publicly available genetic data to prioritize lipid modifying therapeutic targets for prevention of coronary heart disease based on dysglycemic risk.

  Tragante V. et al, (2016), Hum Genet, 135, 453 - 467

• Plasma urate concentration and risk of coronary heart disease: a Mendelian randomisation analysis.

  White J. et al, (2016), Lancet Diabetes Endocrinol, 4, 327 - 336

• Validity of COPD diagnoses reported through nationwide health insurance systems in the People's Republic of China.

  Kurmi OP. et al, (2016), Int J Chron Obstruct Pulmon Dis, 11, 419 - 430

• Deciphering the Causal Role of sPLA2s and Lp-PLA2 in Coronary Heart Disease.

  Talmud PJ. and Holmes MV., (2015), Arterioscler Thromb Vasc Biol, 35, 2281 - 2289

• Harnessing publicly available genetic data to prioritize therapeutic targets for cardiovascular prevention

  Holmes MV. et al, (2015), EUROPEAN HEART JOURNAL, 36, 293 - 294

• A Mendelian Randomization Study of Circulating Uric Acid and Type 2 Diabetes.

  Sluijs I. et al, (2015), Diabetes, 64, 3028 - 3036

• Mendelian randomization of blood lipids for coronary heart disease.

  Holmes MV. et al, (2015), Eur Heart J, 36, 539 - 550

• Association between alcohol and cardiovascular disease: Mendelian randomisation analysis based on individual participant data.

  Holmes MV. et al, (2014), BMJ, 349

• Gene-centric meta-analysis in 87,736 individuals of European ancestry identifies multiple blood-pressure-related loci.

  Tragante V. et al, (2014), Am J Hum Genet, 94, 349 - 360

• Secretory phospholipase A(2)-IIA and cardiovascular disease: a mendelian randomization study.

  Holmes MV. et al, (2013), J Am Coll Cardiol, 62, 1966 - 1976

• Large-scale gene-centric meta-analysis across 32 studies identifies multiple lipid loci.

  Asselbergs FW. et al, (2012), Am J Hum Genet, 91, 823 - 838

• Blood pressure loci identified with a gene-centric array.

  Johnson T. et al, (2011), Am J Hum Genet, 89, 688 - 700

Recent Publications

• Association of Body Mass Index With Cardiometabolic Disease in the UK Biobank: A Mendelian Randomization Study.

  Lyall DM. et al, (2017), JAMA Cardiol

• Relations between lipoprotein(a) concentrations, LPA genetic variants, and the risk of mortality in patients with established coronary heart disease: a molecular and genetic association study.

  Zewinger S. et al, (2017), Lancet Diabetes Endocrinol, 5, 534 - 543

• Causal Associations of Adiposity and Body Fat Distribution With Coronary Heart Disease, Stroke Subtypes, and Type 2 Diabetes Mellitus: A Mendelian Randomization Analysis.

  Dale CE. et al, (2017), Circulation, 135, 2373 - 2388

• Mendelian randomisation in cardiovascular research: an introduction for clinicians.

  Bennett DA. and Holmes MV., (2017), Heart

• Mendelian randomization in cardiometabolic disease: challenges in evaluating causality.

  Holmes MV. et al, (2017), Nat Rev Cardiol