Dr Koen Pouwels
Koen joined HERC as a senior researcher in January 2019. His current work focuses on infectious disease and antimicrobial resistance modelling, randomised trial designs, economic evaluations alongside trials, incorporating long-term effects into economic evaluations, and statistical approaches to address time-dependent confounding in burden of illness studies.
Koen is a member of the Healthcare Associated Infectious Working Group of the Joint Committee on Vaccination and Immunisation (JCVI). His work has directly informed national vaccination and immunisation policies, as well as national targets for antibiotic prescribing in primary care.
Prior to joining HERC, Koen worked at Public Health England on projects using mathematical, statistical and machine learning approaches to understand and predict the development and health-economic impact of healthcare associated infections and antimicrobial resistance. Before coming to the UK, he obtained his PhD in epidemiology at the University of Groningen where he was also involved in a number of economic evaluations of vaccinations against infectious diseases.
Do variations in primary care practice characteristics explain the effect of a financial incentive scheme on antibiotic prescribing? A longitudinal study of the Quality Premium intervention in NHS England.
POUWELS K. et al, (2020), BJGP Open
Estimating the effect of healthcare-associated infections on excess length of hospital stay using inverse-probability weighted survival curves.
Pouwels KB. et al, (2020), Clin Infect Dis
Quantifying the economic cost of antibiotic resistance and the impact of related interventions: rapid methodological review, conceptual framework and recommendations for future studies
Jit M. et al, (2020), BMC Medicine
The health and cost burden of antibiotic resistant and susceptible Escherichia coli bacteraemia in the English hospital setting: A national retrospective cohort study
Naylor NR. et al, (2019), PLOS ONE, 14, e0221944 - e0221944
Machine-learning-assisted selection of antibiotic prescription.
Didelot X. and Pouwels KB., (2019), Nat Med