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Record linkage and bioinformatics 1

Module leads

Michael Goldacre Michael Goldacre

Martin Landray Martin Landray

Learning objective:

  • To understand the role of linkage to routine healthcare and other data sources for population health research, including evaluation of the causes and consequences, prevention and treatment of disease. The module will explore the principles and methods used and will provide a grounding in both the technical (e.g. statistical, epidemiological) and the non-technical (e.g. ethical, regulatory) aspects of this approach.


  1. Introduction to sources, content and uses of routine data for population health science
  2. Information governance
  3. Record linkage and data processing
  4. Data processing and analysis
  5. Generating information on phenotype
  6. The use of routine data for efficient randomised trials
  7. Utilising information technology for large-scale clinical research