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Infants in the Australian and UK Benefits of Oxygen Saturation Targeting-II trials treated using revised oximeters spent more time within their planned pulse oximeter saturation target ranges than infants treated using the original oximeters (P < .001). This may explain the larger mortality difference seen with revised oximeters. If so, average treatment effects from the Neonatal Oxygen Prospective Meta-analysis trials may be underestimates.

Original publication




Journal article


J Pediatr

Publication Date



blindness/epidemiology, blindness/etiology, cerebral palsy/epidemiology, enterocolitis, necrotizing/epidemiology, enterocolitis, necrotizing/etiology, humans, incidence, infant, infant mortality, infant, extremely premature, infant, newborn, oximetry, oxygen/administration & dosage, oxygen/adverse effects, oxygen/blood, trial