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The International Network of Obstetric Survey Systems (INOSS) is a multi-country collaboration formed to facilitate studies of uncommon and severe complications of pregnancy and childbirth. Collaborations such as INOSS offer many benefits in the study of rare complications. The use of uniform case definitions, common datasets, specifically collected detailed data and prospectively agreed comparative and combined analyses all add to the validity of studies and their utility to guide policy and clinical practice and hence improve the quality of care. Such multi-national collaborations allow for the conduct of robust studies less subject to many of the biases attributed to typical observational studies. For very rare conditions such collaborations may provide the only route to providing high quality evidence to guide practice. Clinicians and researchers conducting studies into rare and severe complications should consider working through a network such as INOSS to maximize the value of their research.

Original publication




Journal article


Acta Obstet Gynecol Scand

Publication Date





127 - 131


Severe maternal morbidity, multi-national, network, observational studies, rare complication, Data Collection, Databases as Topic, Evidence-Based Medicine, Female, Humans, International Cooperation, Multicenter Studies as Topic, Obstetric Labor Complications, Pregnancy, Pregnancy Complications, Registries