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INTRODUCTION: Generalized anxiety disorder (GAD) is one of the most common anxiety disorders in later life, with widespread consequences for individuals and society. OBJECTIVE: To perform a systematic review of the efficacy of controlled interventions for GAD in adults aged 55 years and older. METHOD: Direct search of digital databases and the main publications on aging and iterative searches of the references from retrieved articles. RESULTS: Twenty-seven trials (14 pharmacological, 13 psychotherapeutic) fulfilled the inclusion criteria, reporting results from 2373 baseline participants. There were no differences between trials in their overall quality. Pooled treatment effects for pharmacological (OR=0.32, 95% CI: 0.18, 0.54) and psychotherapeutic (OR=0.33, 95% CI: 0.17, 0.66) trials were similar, with findings in each case favoring active interventions over control conditions. CONCLUSIONS: Older adults with GAD benefited from both pharmacological and psychotherapeutic interventions. Future studies should investigate combined treatment with medication and psychotherapy.

Original publication

DOI

10.1016/j.janxdis.2011.08.010

Type

Journal article

Journal

J Anxiety Disord

Publication Date

01/2012

Volume

26

Pages

1 - 11

Keywords

Aged, Aged, 80 and over, Anti-Anxiety Agents, Anxiety Disorders, Combined Modality Therapy, Humans, Middle Aged, Psychotherapy, Treatment Outcome